Bilateral synchronous occurrence of three different histological types of renal tumor: a case report

Abstract:

Introduction: Renal cell carcinomas account for 85% of all renal neoplasms. With the introduction of modern imaging modalities, there has been an increased diagnosis of renal tumors. Recent studies have shown that partial nephrectomy can be as safe as radical nephrectomy for smaller renal tumors. Renal cell carcinomas are usually unilateral, however, they can be bilateral in 2% to 4% of sporadic cases and considerably more common in familial cases.

Case presentation: In this case report, we describe an unusual case of two bilateral synchronous chromophobe renal cell carcinomas accompanied by an oncocytoma and an angiomyolipoma, that were all treated by open partial nephrectomy.

Conclusions: To the best of our knowledge, this is the first case report on the synchronous occurrence of bilateral chromophobe renal cell carcinomas associated with an oncocytoma and an angiomyolipoma.

Introduction
Renal cell carcinoma (RCC) accounts for 85% of all renal neoplasms. Its incidence has been rising due to the increased use of ultrasonography and computed tomography (CT) scans for the evaluation of patients with a diversity of presenting symptoms. Most renal cell carcinomas are unilateral, but bilateral tumors, synchronous or asynchronous, have been found in 2% to 4% of reported sporadic cases. However, the incidence is higher among patients suffering from Von Hippel-Lindau (VHL) disease and other familial cases. Radical nephrectomy is considered the standard treatment modality for renal cell carcinomas. However, recent data have shown that partial nephrectomy is as safe and effective as radical nephrectomy for tumors smaller than 4 cm, andmore recent studies support the fact that the indications for partial nephrectomy can be safely extended to tumors up to 7cm. In this case report, we describe an unusual sporadic case of bilateral synchronous RCC accompanied by an oncocytoma and an angiomyolipoma that were all treated by open partial nephrectomy.

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