With the increasing number of long-term survivors who have been treated with newer anticancer therapy strategies, we encounter increasing numbers of sequelae from earlier therapeutic approaches. These long-term side effects are an important factor in the patient's quality of life, both psychologically and somatically, and must be addressed in the treatment of the underlying disease.
Radiation-induced fibroatrophy (RIF) is a rare late sequela of high-dose radiation therapy. It is localized to the radiation field and is usually irreversible. The pathologic manifestation of this entity can be limited to skin dryness, hyperpigmentation or telangiectasia. This superficial damage, however, may also be combined with underlying fibronecrotic lesions affecting the pleura and lungs resulting in pulmonary fibrosis, neurological disorders secondary to the development of perineural fibrosis, or spontaneous rib fractures due to osteoradionecrosis 1-3. We report the excellent cosmetic and functional results after surgical treatment in a particular clinical setting of pseudotumoral radionecrosis as a late radiation-induced injury after initial anticancer treatment.