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Evolution of the 21-gene Assay Oncotype DX® from an Experimental Assay to an Instrument Assisting in Risk Prediction and Optimisation of Treatment Decision-making in Early Breast Cancer

In general, mortality due to breast cancer is declining almost everywhere in the world. However, one of the few published reports on the current...

Association between thymoma and persistent hypothermia: a case report

Introduction The thymus is a small anterosuperior mediastinal organ involved in the processing and maturation of T lymphocytes. The thymus gland...

Developments in Breast Cancer Treatment – Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 Inhibitors

EGFR and HER-2 in Breast Cancer The EGFR/HER family of tyrosine kinases plays an important role in the development and progression of breast...

Novel Treatment Approaches for Managing Early-stage Breast Cancer – Maximising Safety and Outcome with Adjuvant Taxane-containing Chemotherapy Regimens

The proportion of EBC (stages 0 and I) increased from 34.2% in 1991 to 48.8% in 2003. In Taiwan, the age-adjusted incidence of invasive breast cancer...

The Challenge of Breast Cancer in Low- and Middle-income Countries – Implementing the Breast Health Global Initiative Guidelines

The prognosis of those with breast cancer is good, although globally it still ranks as the leading cause of cancer mortality among women. Favourable...

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