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Marwan Fakih discusses the implications of primary tumour location on biological therapy in metastatic colorectal cancer.
Part 2 of 2 – Dr Marc Peeters, from our European Editorial Board, explains the move from treating patients with BRAF-targeting drugs, to using combination therapy to target the EGFR pathway in BRAF-mutant mCRC. He also discusses the BEACON CRC study, which uses this combination of binimetinib, encorafenib, and cetuximab to treat BRAF-mutant tumors. Speaker disclosures: BEACON trial...
Part 1 of 2 – Dr Marc Peeters, from our European Editorial Board, summarizes the clinical use of circulating tumor DNA in colorectal cancer (CRC). He also discusses the difficulties of making interstudy comparisons between the outcomes of second-line trials in metastatic CRC. Speaker disclosures: BEACON trial investigator. Filmed at the American Society of Clinical Oncology (ASCO) Annual...