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Based on the results of the phase I part of the study, eight (19%) of the 42 evaluable patients responded to the anti-PD-1 antibody with tumour reduction beyond 30%. More importantly, the responses have been durable and surpassed 12 months in four patients. The overall survival rate at 12 months was 62%.
After local chemotherapy of the liver, the catheter filters out excess drug that is prevented from travelling to the rest of the body. This minimizes the potential for toxic side effects and may allow the use of higher local doses that increase treatment efficacy.
Sarah Cannon Radiation Oncology Physician-in-Chief Andrew Kennedy, M.D., discusses metastatic colorectal cancer and answers participants' questions during this CancerConnect Web Chat with the Experts titled, "Using Radiation to Treat Colorectal Cancers Metastasized to the Liver." During the web chat, Dr. Kennedy discusses mCRC treatment options including Selective Internal Radiation Therapy...