1st February 2005
Finnish Medical Society Duodecim - Professional Association
Summary,


GUIDELINE OBJECTIVE(S)

Evidence-Based Medicine Guidelines collect, summarize, and update the core clinical knowledge essential in general practice. The guidelines also describe the scientific evidence underlying the given recommendations.

TARGET POPULATION

• Patients with symptoms of adenomatous polyps or colorectal cancer
• Asymptomatic persons with increased risk for colorectal cancer

INTERVENTIONS AND PRACTICES CONSIDERED

Screening/Prevention

1. Detection and follow-up of adenomas for symptomatic patients and asymptomatic persons at increased risk
   • Colonography
   • Colonoscopy
   • Polyp removal as indicated
2. Preventive measures (e.g., diet)
3. Screening family members of cancer patients
4. Examination of symptomatic patients

Interventions considered by not specifically recommended:

1. Population-based screening with faecal occult blood testing (FOBT)
2. Preventive strategies such as dietary fibre, garlic, dietary calcium, and antioxidant supplements

MAJOR OUTCOMES CONSIDERED

• Mortality from colorectal cancer
• Neoplasms, adenomas, and malignancies detected through screening
• Screening adherence rates
• Harmful effects of screening
• Effectiveness of preventive strategies