Articles
Accelerated Partial Breast Irradiation for Early-stage, Low-risk Breast Cancer
The reason that so few women choose BCT is largely due to the inconvenience of attending six to seven weeks of daily radiation treatments (RT). Often...
Adjuvant Treatment of Breast Cancer in Older Patients
Surgery is the primary treatment of choice in early-stage breast cancer for patients of all ages. Older patients who do not undergo surgical removal...
Answers and Remaining Questions Regarding Systemic Treatments for Breast Cancer in the Elderly
Endocrine Treatments Late diagnosis and substandard local and systemic therapies are common in elderly breast cancer patients, which is only...
Aromatase Inhibitors - The New Standard for Postmenopausal Women with Hormone-responsive Breast Cancer
Aromatase Inhibitors In postmenopausal women – in whom hormone responsiveness is common – oestrogen is primarily synthesised...
Aromatase Inhibitors in Metastatic Breast Cancer
Anti-oestrogen therapy with tamoxifen has been the standard first-line treatment for postmenopausal women with hormone receptor-positive (HR+) ABC...
Association between thymoma and persistent hypothermia: a case report
Introduction The thymus is a small anterosuperior mediastinal organ involved in the processing and maturation of T lymphocytes. The thymus gland...
Bone Metastases in Breast Cancer
Patients with advanced breast cancer are at high risk for developing bone metastases and ensuing skeletal complications. Since the mid 1990s,...
Breast Cancer and Novel Therapeutic Treatments
Biological Models In accordance with Fisher's hypothesis of biological pre-determinism, these micrometastatic foci can remain dormant and be...
Breast Preserving Therapy with Single Fraction Intraoperative Radiotherapy
Data from the Surveillance Epidemiology and End Results (SEER) registry demonstrate that the percentage of patients receiving appropriate...
Controlling Breast Cancer
Treatment Prospects have improved with the development of new drugs that interfere with unique biochemical pathways driven by cancer-causing...
Cryoablation of Early-stage Breast Cancer
The History of Cryosurgery Cryosurgery has already been used successfully in treating primary and metastatic liver tumors3 and prostate cancer.4 Its...
Current Challenges in Human Epidermal Growth Factor Receptor-2-positive Breast Cancer - Treating Disease Progression
Trastuzumab is a recombinant humanised monoclonal antibody directed against the extracellular domain of the HER-2 protein. There are several...
Developments in Breast Cancer Treatment – Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 Inhibitors
EGFR and HER-2 in Breast Cancer The EGFR/HER family of tyrosine kinases plays an important role in the development and progression of breast...
Ductoscopy-guided and Conventional Surgical Excision
When mammography shows significant findings in women with SND, the likelihood of malignancy increases,2 but mammographic imaging is often unhelpful....
Evolution of the 21-gene Assay Oncotype DX® from an Experimental Assay to an Instrument Assisting in Risk Prediction and Optimisation of Treatment Decision-making in Early Breast Cancer
In general, mortality due to breast cancer is declining almost everywhere in the world. However, one of the few published reports on the current...
Intra-operative Radiotherapy for Early Breast Cancer
Figure 1: RT After BCS May Become More Risk-adapted in the FutureIORT = intra-operative radiotherapy,WBRT = whole breast radiotherapy. Challenging...
Magnetic Resonance Imaging Gaining Importance in Breast Cancer High-risk Screening and Disease Management
High-risk women include those who have had a previous breast cancer or other high-risk histologies, those with a strong family history of breast...
Metastatic Breast Cancer - Opportunities from Novel Diagnostic Modalities
Despite years of clinical research, the odds of achieving complete resolution of metastatic disease with current treatment strategies remain low.2-4...
Novel Pharmacodiagnostics in Breast Cancer
However, despite significant research efforts over the past 20 years, with literally hundreds of thousands of research publications relating to...
Novel Treatment Approaches for Managing Early-stage Breast Cancer – Maximising Safety and Outcome with Adjuvant Taxane-containing Chemotherapy Regimens
The proportion of EBC (stages 0 and I) increased from 34.2% in 1991 to 48.8% in 2003. In Taiwan, the age-adjusted incidence of invasive breast cancer...
