John Marshall, MD, is a global leader in the research and development of drugs for colon cancer and other gastrointestinal cancers. He has been the principal investigator of over 150 clinical trials at local, as well as national, levels. Dr Marshall is the clinical director of oncology for Georgetown University Hospital, associate director for clinical care of the Lombardi Comprehensive Cancer Center, and chief of the Division of Hematology-Oncology. In 2009, Dr Marshall became the founding director of the Otto J Ruesch Center for the Cure of Gastrointestinal Cancers. Combining expertise in molecular medicine, translational research, and a patient-centered philosophy, the Ruesch Center is dedicated to realizing the dream of individualized curative therapies through research, care, and advocacy.