Welcome to the Fall edition of Oncology & Hematology Review (US). This edition, expertly introduced by Shaji Kumar, features a wide range of timely and concise review articles on some of the most important topics in the field including breast cancer, cervical cancer, gastrointestinal cancer, genitourinary cancer, and hematologic malignancies. In the lung cancer section Dr Fenton explores current and future therapeutics for patients with non-small cell lung cancer and known activating mutations in EGFR, and Scagliotti and Novello focus on the investigational new agent rociletinib in the same patient set. Dr Warner discusses the important topic of knowledge management for oncologists and Friedman and Postow discuss the latest developments in managing immunotherapy-related side effects. We hope this collection of topical articles provide useful information relevant to your practice and interests.